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Following 4 days of dosing with 6 tablets of levocarnitine 330 mg twice daily or 2 g of levocarnitine oral solution twice daily, the maximum plasma concentration (Cmax) was about 80 mol/L and the time to maximum plasma concentration (Tmax) occurred at 3.3 hours

doi: 10.1016/j.autrev.2023.103297 54 PanQ.GuoF.HuangY.LiA.ChenS.ChenJ.et al

However, the nave, unstable PKC molecule has a strong affinity for constitutively active kinases (i.e., PDK 1 ), and undergoes maximum phosphorylation at its activation site (i.e., P A ) as a result (Figure 1, reaction event R 4 )