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In fact, ATP reduction and its relation to oxidative stress have been linked not only to depression (detailed below), but also to psychotic disorders (see Chouinard et al., 2017), autism (Rose et al., 2014), anxiety (Kumar and Chanana, 2017), Alzheimers disease (recently reviewed in Tramutola et al., 2017), and Huntington disease (Quintanilla et al., 2017)

Autophagy 5(2):280282 Yang L, Li P, Fu S et al (2010) Defective hepatic autophagy in obesity promotes ER stress and causes insulin resistance

However, others propose that respiratory inhibition negatively affects ATP production via subsequent effects on mitochondrial depolarization ( Alternatively, there is the notion that NO advantageously affects mitochondrial efficiency (Pappas et al., 2023)

For instance, studies in laboratory rodents have found that dietary omega-3 PUFA deficiency impaired measures of cognitive performance through influencing the dopamine neurotransmitter system in the frontal cortex region of the brain (98)