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More than 100 years later, it is still trying to solve practical workplace challenges

Tobacco In recent years, more and more attention has been paid to the upgrading of the curing barns and the development of alternative energy sources of coal in the wake of the development of modern tobacco agriculture

Here, we provide evidence that PINK1/Parkin-mediated mitophagy is impaired in the hippocampus of AD patients, in induced pluripotent stem cell-derived human AD neurons, and in animal AD models, that impaired removal of defective mitochondria is a pivotal event in AD pathogenesis and that mitophagy represents a potential therapeutic intervention [32]