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Clinical parameters An automated hematology analyzer XE-2100 (Sysmex, Kobe, Japan) was used for the determination of Hemoglobin (Hb)

However, the high sequence identity (53%) and the same active site shared between human fumarase and Mtb fumarase pose a challenge in developing anti-tuberculosis drugs targeting this enzyme [287]

Similar to other GLP-1 drugs, CagriSema had mild to moderate side effects, which were mainly gastrointestinal (including nausea, vomiting, diarrhea, and constipation) and diminished over time