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Reduces the Risk of Macular (Eye) Degeneration Age-related macular degeneration (AMD) is more than twice as common in individuals with a Vitamin B12 deficiency than in those with healthy levels of Vitamin B12

As we have stated in previous rulemaking (75 FR 72064 and 76 FR 74494), consensus among affected parties can be reflected in ways other than CBE endorsement, including through the measure development process, through broad acceptance and use of the measure(s), and through public comment

Cheleschi, S

Furthermore, low B12 has been linked to higher levels of homocysteine, which is associated with increased bone loss and joint inflammation