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X-ray crystallography provides a structural rationale for photoactivation in photocobilins To provide a structural rationale for the photocobilin photo-sensing properties, we determined the crystal structures of the dark (PDB 8J2W) and light-adapted states (PDB 8J2X) of Sas Pcob, as well as the dark state of the isolated Ab DPcob photoreceptor domain ( Ab Pcob, PDB 8J2Y), at 1.7 ;, 2.0

This model was used by our team for nanoparticle studies [24], and its BBB properties were further enhanced by targeting signaling pathways with cARLA [40]