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10.1002/adma.202004647 15 ChehelgerdiM.ChehelgerdiM.AllelaO

In Vivo Models Effects on Inflammatory Cytokines and NLRP3 Inflammasome Caspase-1 Signaling Tetracyclines significantly reduce the secretion of pro-inflammatory cytokines, including TNF-, IL-1, IL-6, and IL-8, thereby improving survival and lung injury in indirect models of ARDS [16, 19, 24]

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It has been reported that SCFAs, chiefly butyrate, possess a neuroprotective effect, they promote anti-inflammatory pathways and enhance mitochondrial function in neuronal cells (123)