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Di-PKM2 interacts with STAT3 and -catenin, regulates the transcription of MEK5, Cyclin D1, GLUT1, and LDHA, induces aerobic glycolysis, and promotes the proliferation, migration, and osteogenesis of VSMCs [98]

Measurement of antioxidant parameters The serum of lactating sows and suckling piglets was used to measure the glutathione (GSH), peroxidase (POD), catalase (CAT), total antioxidant capacity (T-AOC), glutathione peroxidase (GSH-Px) activity, and malondialdehyde (MDA) content using commercially available kits (Shanghai Zhuocai, China) following the manufacturer's instructions

It can be applied topically, it can be inhaled, and it can be administered through an IV in severe cases