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According to Sev transcriptional sequencing, the expression of ferroptosis- and mitophagy-related gene-activating transcription factor 4 (ATF4) was enhanced, and Sev induced ferroptosis in glioma cells by activating the ATF4-CHAC1 pathway (Xu et al., 2022)

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Genome-Wide Significant Predictors of Metabolites in the One-Carbon Metabolism Pathway. Human Molecular Genetics, vol

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In contrast, suppression of GSTP activity downregulates cell proliferation for infinitely proliferative cells including cancer cells

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