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ROS drive HIF-1-BNIP3/NIX-mediated mitophagy and alleviate cell apoptosis and inflammation in M9a+sh EPAS1 cells during hypoxia To identify the cause of induced mitophagy, we explored the role of ROS, given their involvement in stabilizing HIF-1 [22, 28]

In this system, changes in real-time gene expression, as a consequence of constitutive G-protein coupling of the orphan HGPRBMY14 GPCR, is examined by analyzing the fluorescence emission of the transformed cells at 447 nm and 518 nm