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In the last hundred years, scientists have understood this mechanism to include lipid peroxidation, hepatotoxicity, and liver damage through CYP2E1-mediated metabolism into toxic trichloromethyl and trichloromethyl peroxyl radicals

Over-the-counter hydroquinone products could be unsafe because they often contain other ingredients that could destabilise it. The Skin Lightening process involves using approved skincare ingredients in safe doses to improve the appearance of the skin, especially where there have been concerns of post-inflammatory hyperpigmentation, melasma or sun damage that can darken the complexion

Iberian pig as a model to clarify obscure points in the bioavailability and metabolism of ellagitannins in humans

Honda et al