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These include intranasal administration, which allows NGF to bypass the BBB and reach brain parenchyma, and the development of NGF-mimetic small molecules or selective TrkA agonists (Rogdakis et al., 2022

10.1515/ijamh-2022-0065 89 NevenA.MousaA.BoyleJ

Short-term glucocorticoid treatment compromises both permeability barrier homeostasis and stratum corneum integrity: inhibition of epidermal lipid synthesis accounts for functional abnormalities