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The model showed midbrain cholesterol accumulation, enhanced triacylglycerol (TAG) hydrolysis, accompanied by DA neuron loss, astrogliosis, increased -syn expression, and significant elevation of lipid peroxidation and ferroptosis markers, correlating with motor deficits (Maniscalchi et al., 2024)

HDL can remove cholesterol from the macrophages of the arterial wall through a number of mechanisms including an active transport mechanism

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