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3.2 RNS in IBD pathogenesis RNS comprise the second category of free radicals, produced as a byproduct of nitric oxide synthases(NOS) and expressed in specific intestinal submucosa and mucosal regions

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In studies evaluating the therapeutic potential of mangiferin in allergic rhinitis, results from an OVA-induced mouse model showed that mangiferin significantly alleviated allergic symptoms, as evidenced by reduced nasal rubbing, sneezing, and eosinophil and mast cell infiltration