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Models are often fit with experimental data to determine parameters, such as the parameters describing transcription and translation kinetics

You may request a visual inspection if you prefer, but its generally not required

Furthermore, Fabio et al

Multiple randomised trials from the 1970s and 1980s have shown its antiparkinsonian efficacy while its antidyskinetic efficacy in PD patients with LIDs was only demonstrated some 30 years after its introduction into PD therapy [13]