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Withaferin A (WA) has been found to not only inhibit the activity of GPX4 in neuroblastoma but also activate heme oxygenase-1 to increase intracellular Fe 3+ concentration, thereby inducing ferroptosis in neuroblastoma [136]

5f, quantification: Fig

Despite being recognized as the primary allergen among shrimp-sensitized individuals, recent findings have reported sensitization rates to Pen m 1 of less than 50%, including 31% in Australian infants [44], 37% in Japanese [45], 42% in Austrian [46], 41.2% in Chinese [47], and 41% in Italian [48] shrimp-allergic populations