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In the Phase 2 trial, 72% of participants who had prediabetes at the start had normal glycated hemoglobin levels at 48 weeks, compared to just 22% on placebo

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N Engl J Med 348:21102124 Carta M, Murru L, Barabino E, Talani G, Sanna E, Biggio G (2008) Isoniazid-induced reduction in GABAergic neurotransmission alters the function of the cerebellar cortical circuit