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1, 2 and 3 represented three randomly picked colonies

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However, it remains unclear how ferroptosis regulates immune cell infiltration in the tumor microenvironment of kidney cancer and how it promotes the transition of M2 macrophages to M1 macrophages

However, activation of LXRs could be a double-edged sword, as LXRs are highly expressed in haematopoietic stem cells and myeloid progenitor cells, in which they decrease the proliferative responses to IL-3 and GM-CSF (Murphy et al., 2011)