ghk-cu copper coordination sites Molecular crystal structure of the tripeptide GHK-Cu. In solution, GHK-CU - Alignpeptides

Copper is essential for the activity of enzymes involved in collagen cross-linking (lysyl oxidase), antioxidant defence (superoxide dismutase), and angiogenesis

Prescription topical GHK-Cu does not require cycling off, because the collagen-stimulating effects reward uninterrupted daily use

Given that cellular function depends critically on precise copper homeostasis, any disturbance in this balance can have severe pathological consequences [11]

To understand the dynamics of this interplay in T1DM, one must go back to the relation between portal insulin and GHR expression on hepatocytes, which was so cleverly addressed by Leung et al