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curcumin The oncogenic pathways inhibited by curcumin include down-regulation of epidermal growth factor receptors (EGFR and erbB2), Insulin- like growth factor type- 1 receptor (IFG-1R), sonic hedgehog (SHH)/GLIs) and Wnt/b-catenin and PARP, IKK, EGFR, JNK, MAPK and 5-LOX

This study demonstrated that -LA supplementation (300 mg/d, twice a day) for 3 months significantly decreased the serum levels of MDA and C-reactive protein (CRP), as two inflammatory and oxidative stress markers, and mood disorders in patients with episodic migraine

14 Creating a reporting system that ensures confidentiality empowers pharmacy staff to come forward with their concerns, enabling prompt intervention